Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

LSAMP_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection . [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in LSAMP_HUMAN
GO:0019900 kinase binding 30.7692 4 no
GO:0015631 tubulin binding 30.7692 4 no
GO:0019901 protein kinase binding 23.0769 5 no
GO:0043169 cation binding 23.0769 4 no
GO:0046872 metal ion binding 23.0769 5 no
GO:0003779 actin binding 23.0769 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in LSAMP_HUMAN
GO:0048522 positive regulation of cellular process 69.2308 4 no
GO:0051128 regulation of cellular component organization 61.5385 4 no
GO:0009893 positive regulation of metabolic process 53.8462 4 no
GO:0010646 regulation of cell communication 53.8462 4 no
GO:0031323 regulation of cellular metabolic process 53.8462 4 no
GO:0031325 positive regulation of cellular metabolic process 53.8462 5 no
GO:0060255 regulation of macromolecule metabolic process 53.8462 4 no
GO:0009966 regulation of signal transduction 46.1538 4 no
GO:0031344 regulation of cell projection organization 46.1538 5 no
GO:0048523 negative regulation of cellular process 46.1538 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 46.1538 6 no
GO:0006996 organelle organization 46.1538 4 no
GO:0010604 positive regulation of macromolecule metabolic process 46.1538 5 no
GO:0022607 cellular component assembly 46.1538 4 no
GO:0051049 regulation of transport 46.1538 4 no
GO:0019220 regulation of phosphate metabolic process 38.4615 6 no
GO:0031399 regulation of protein modification process 38.4615 6 no
GO:0042325 regulation of phosphorylation 38.4615 7 no
GO:0043549 regulation of kinase activity 38.4615 5 no
GO:0043933 protein-containing complex organization 38.4615 4 no
GO:0050804 modulation of chemical synaptic transmission 38.4615 5 no
GO:0051174 regulation of phosphorus metabolic process 38.4615 5 no
GO:0051246 regulation of protein metabolic process 38.4615 5 no
GO:0051338 regulation of transferase activity 38.4615 4 no
GO:0065003 protein-containing complex assembly 38.4615 5 no
GO:0080090 regulation of primary metabolic process 38.4615 4 no
GO:0099177 regulation of trans-synaptic signaling 38.4615 4 no
GO:0009889 regulation of biosynthetic process 38.4615 4 no
GO:0010468 regulation of gene expression 38.4615 6 no
GO:0010556 regulation of macromolecule biosynthetic process 38.4615 5 no
GO:0010959 regulation of metal ion transport 38.4615 6 no
GO:0031326 regulation of cellular biosynthetic process 38.4615 5 no
GO:0043269 regulation of monoatomic ion transport 38.4615 5 no
GO:0051924 regulation of calcium ion transport 38.4615 7 no
GO:0001932 regulation of protein phosphorylation 30.7692 7 no
GO:0009892 negative regulation of metabolic process 30.7692 4 no
GO:0009968 negative regulation of signal transduction 30.7692 5 no
GO:0010562 positive regulation of phosphorus metabolic process 30.7692 6 no
GO:0010563 negative regulation of phosphorus metabolic process 30.7692 6 no
GO:0010605 negative regulation of macromolecule metabolic process 30.7692 5 no
GO:0010648 negative regulation of cell communication 30.7692 5 no
GO:0023057 negative regulation of signaling 30.7692 4 no
GO:0030030 cell projection organization 30.7692 4 no
GO:0031324 negative regulation of cellular metabolic process 30.7692 5 no
GO:0031400 negative regulation of protein modification process 30.7692 7 no
GO:0032880 regulation of protein localization 30.7692 5 no
GO:0033674 positive regulation of kinase activity 30.7692 6 no
GO:0042326 negative regulation of phosphorylation 30.7692 8 no
GO:0042327 positive regulation of phosphorylation 30.7692 8 no
GO:0042981 regulation of apoptotic process 30.7692 5 no
GO:0043066 negative regulation of apoptotic process 30.7692 6 no
GO:0043067 regulation of programmed cell death 30.7692 4 no
GO:0043069 negative regulation of programmed cell death 30.7692 5 no
GO:0043085 positive regulation of catalytic activity 30.7692 4 no
GO:0045859 regulation of protein kinase activity 30.7692 6 no
GO:0045936 negative regulation of phosphate metabolic process 30.7692 7 no
GO:0045937 positive regulation of phosphate metabolic process 30.7692 7 no
GO:0048585 negative regulation of response to stimulus 30.7692 4 no
GO:0050807 regulation of synapse organization 30.7692 5 no
GO:0050890 cognition 30.7692 4 no
GO:0051129 negative regulation of cellular component organization 30.7692 5 no
GO:0051247 positive regulation of protein metabolic process 30.7692 6 no
GO:0051248 negative regulation of protein metabolic process 30.7692 6 no
GO:0051347 positive regulation of transferase activity 30.7692 5 no
GO:0060341 regulation of cellular localization 30.7692 4 no
GO:0120036 plasma membrane bounded cell projection organization 30.7692 5 no
GO:1902531 regulation of intracellular signal transduction 30.7692 5 no
GO:1903829 positive regulation of protein localization 30.7692 5 no
GO:0010975 regulation of neuron projection development 30.7692 7 no
GO:0044087 regulation of cellular component biogenesis 30.7692 4 no
GO:0051130 positive regulation of cellular component organization 30.7692 5 no
GO:0022603 regulation of anatomical structure morphogenesis 30.7692 4 no
GO:0007010 cytoskeleton organization 30.7692 5 no
GO:0034330 cell junction organization 30.7692 4 no
GO:0034762 regulation of transmembrane transport 30.7692 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 30.7692 5 no
GO:1903169 regulation of calcium ion transmembrane transport 30.7692 7 no
GO:1904062 regulation of monoatomic cation transmembrane transport 30.7692 6 no
GO:1904064 positive regulation of cation transmembrane transport 23.0769 7 no
GO:1904427 positive regulation of calcium ion transmembrane transport 23.0769 7 no
GO:0001933 negative regulation of protein phosphorylation 23.0769 8 no
GO:0001934 positive regulation of protein phosphorylation 23.0769 8 no
GO:0009890 negative regulation of biosynthetic process 23.0769 5 no
GO:0010038 response to metal ion 23.0769 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 23.0769 6 no
GO:0030162 regulation of proteolysis 23.0769 6 no
GO:0031327 negative regulation of cellular biosynthetic process 23.0769 6 no
GO:0031401 positive regulation of protein modification process 23.0769 7 no
GO:0031648 protein destabilization 23.0769 4 no
GO:0043065 positive regulation of apoptotic process 23.0769 6 no
GO:0043068 positive regulation of programmed cell death 23.0769 5 no
GO:0043523 regulation of neuron apoptotic process 23.0769 6 no
GO:0045860 positive regulation of protein kinase activity 23.0769 7 no
GO:0050848 regulation of calcium-mediated signaling 23.0769 6 no
GO:0051259 protein complex oligomerization 23.0769 6 no
GO:1904375 regulation of protein localization to cell periphery 23.0769 6 no
GO:1904377 positive regulation of protein localization to cell periphery 23.0769 6 no
GO:0031175 neuron projection development 23.0769 6 no
GO:0031346 positive regulation of cell projection organization 23.0769 6 no
GO:0006915 apoptotic process 23.0769 4 no
GO:0050808 synapse organization 23.0769 5 no
GO:0033673 negative regulation of kinase activity 23.0769 6 no
GO:0043086 negative regulation of catalytic activity 23.0769 4 no
GO:0046903 secretion 23.0769 4 no
GO:0051348 negative regulation of transferase activity 23.0769 5 no
GO:0010647 positive regulation of cell communication 23.0769 5 no
GO:0023056 positive regulation of signaling 23.0769 4 no
GO:0048584 positive regulation of response to stimulus 23.0769 4 no
GO:0009894 regulation of catabolic process 23.0769 4 no
GO:0010506 regulation of autophagy 23.0769 6 no
GO:0010638 positive regulation of organelle organization 23.0769 6 no
GO:0031329 regulation of cellular catabolic process 23.0769 5 no
GO:0033043 regulation of organelle organization 23.0769 5 no
GO:0044089 positive regulation of cellular component biogenesis 23.0769 5 no
GO:0051336 regulation of hydrolase activity 23.0769 4 no
GO:0008104 protein localization 23.0769 4 no
GO:0009891 positive regulation of biosynthetic process 23.0769 5 no
GO:0022898 regulation of transmembrane transporter activity 23.0769 4 no
GO:0031328 positive regulation of cellular biosynthetic process 23.0769 6 no
GO:0034764 positive regulation of transmembrane transport 23.0769 5 no
GO:0034767 positive regulation of monoatomic ion transmembrane transport 23.0769 6 no
GO:0043270 positive regulation of monoatomic ion transport 23.0769 5 no
GO:0044057 regulation of system process 23.0769 4 no
GO:0051050 positive regulation of transport 23.0769 4 no
GO:0051279 regulation of release of sequestered calcium ion into cytosol 23.0769 5 no
GO:0051282 regulation of sequestering of calcium ion 23.0769 4 no
GO:0051928 positive regulation of calcium ion transport 23.0769 6 no
GO:0061024 membrane organization 23.0769 4 no
GO:0071702 organic substance transport 23.0769 4 no
GO:0071705 nitrogen compound transport 23.0769 4 no
GO:0007399 nervous system development 15.3846 4 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
ANK2_HUMAN [view entry] [view interactions] High throughput yes yes
CD248_HUMAN [view interactions] High throughput no no
LRC61_HUMAN [view interactions] High throughput no yes
THAP3_HUMAN [view interactions] High throughput no yes
MET27_HUMAN [view interactions] High throughput no yes
CENPV_HUMAN [view interactions] High throughput no yes
H3C_HUMAN [view interactions] High throughput no yes
ELK3_HUMAN [view interactions] High throughput no yes
SMRD1_HUMAN [view interactions] High throughput no yes
BECN1_HUMAN [view interactions] High throughput no yes
MED21_HUMAN [view interactions] High throughput no yes
DELE1_HUMAN [view interactions] High throughput no yes
CENPR_HUMAN [view interactions] High throughput no yes
NEGR1_HUMAN [view entry] [view interactions] High throughput yes yes
LSAMP_HUMAN [view entry] [view interactions] High throughput yes no
NTRI_HUMAN [view entry] [view interactions] High throughput yes yes
KTU_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
EPB41_HUMAN [view entry] [view interactions] High throughput yes no