PLPR4_HUMAN
Evidence for PS localization
Functions
Hydrolyzes lysophosphatidic acid (LPA) and participates to the axonal outgrowth during development by attenuating phospholipid-induced axon collapse in neuron. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in PLPR4_HUMAN |
|---|---|---|---|---|
| GO:0042803 | protein homodimerization activity | 40.0000 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in PLPR4_HUMAN |
|---|---|---|---|---|
| GO:0006796 | phosphate-containing compound metabolic process | 60.0000 | 4 | yes |
| GO:0006644 | phospholipid metabolic process | 40.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 40.0000 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 40.0000 | 5 | yes |
| GO:0071702 | organic substance transport | 40.0000 | 4 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 40.0000 | 4 | yes |
| GO:0090407 | organophosphate biosynthetic process | 40.0000 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| TRI67_HUMAN | [view interactions] | Low throughput | no | no |
| GLU2B_HUMAN | [view interactions] | Low throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F10C1_HUMAN | [view interactions] | High throughput | no | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUF7_HUMAN | [view interactions] | High throughput | no | yes |
| F91A1_HUMAN | [view interactions] | High throughput | no | yes |
| NECT2_HUMAN | [view interactions] | High throughput | no | no |
| ZNRF3_HUMAN | [view interactions] | High throughput | no | no |
| DCAKD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPAP1_HUMAN | [view interactions] | High throughput | no | no |
| MIB2_HUMAN | [view interactions] | High throughput | no | yes |
| DESI1_HUMAN | [view interactions] | High throughput | no | yes |
| PLPR1_HUMAN | [view interactions] | High throughput | no | no |
| DGAT2_HUMAN | [view interactions] | Computational | no | no |
| PLCC_HUMAN | [view interactions] | Computational | no | no |
| MBOA5_HUMAN | [view interactions] | Computational | no | no |
| LCLT1_HUMAN | [view interactions] | Computational | no | no |
| PLCD_HUMAN | [view interactions] | Computational | no | yes |
| LPCT4_HUMAN | [view interactions] | Computational | no | yes |
| PLCB_HUMAN | [view interactions] | Computational | no | yes |
| PLCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MBOA2_HUMAN | [view interactions] | Computational | no | yes |
| MBOA7_HUMAN | [view interactions] | Computational | no | no |
| DGAT1_HUMAN | [view interactions] | Computational | no | yes |
| MOGT1_HUMAN | [view interactions] | Computational | no | no |
| MOGT3_HUMAN | [view interactions] | Computational | no | yes |
| PLCA_HUMAN | [view interactions] | Computational | no | yes |
| MBOA1_HUMAN | [view interactions] | Computational | no | no |