Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PALM2_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

[View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in PALM2_HUMAN
GO:0017076 purine nucleotide binding 55.5556 4 no
GO:0032555 purine ribonucleotide binding 51.8519 4 no
GO:0035639 purine ribonucleoside triphosphate binding 51.8519 4 no
GO:0019900 kinase binding 48.1481 4 no
GO:0019901 protein kinase binding 48.1481 5 no
GO:0003924 GTPase activity 40.7407 7 no
GO:0005525 GTP binding 40.7407 5 no
GO:0016462 pyrophosphatase activity 40.7407 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 40.7407 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 40.7407 6 no
GO:0019001 guanyl nucleotide binding 40.7407 5 no
GO:0032561 guanyl ribonucleotide binding 40.7407 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in PALM2_HUMAN
GO:0048522 positive regulation of cellular process 85.1852 4 no
GO:0022607 cellular component assembly 62.9630 4 no
GO:0051049 regulation of transport 62.9630 4 no
GO:0060255 regulation of macromolecule metabolic process 62.9630 4 no
GO:0006996 organelle organization 62.9630 4 no
GO:0051128 regulation of cellular component organization 59.2593 4 no
GO:0008104 protein localization 55.5556 4 no
GO:0009893 positive regulation of metabolic process 55.5556 4 no
GO:0010604 positive regulation of macromolecule metabolic process 55.5556 5 no
GO:0010646 regulation of cell communication 55.5556 4 no
GO:0030030 cell projection organization 51.8519 4 no
GO:0007010 cytoskeleton organization 51.8519 5 no
GO:0048584 positive regulation of response to stimulus 48.1481 4 no
GO:0010468 regulation of gene expression 48.1481 5 no
GO:0016192 vesicle-mediated transport 48.1481 4 no
GO:0048523 negative regulation of cellular process 48.1481 4 no
GO:0009966 regulation of signal transduction 48.1481 4 no
GO:0080090 regulation of primary metabolic process 48.1481 4 no
GO:0031323 regulation of cellular metabolic process 44.4444 4 no
GO:0022603 regulation of anatomical structure morphogenesis 44.4444 4 yes
GO:0071702 organic substance transport 44.4444 4 no
GO:0030334 regulation of cell migration 44.4444 5 no
GO:0051171 regulation of nitrogen compound metabolic process 44.4444 4 no
GO:0071310 cellular response to organic substance 44.4444 4 no
GO:1902531 regulation of intracellular signal transduction 44.4444 5 no
GO:2000145 regulation of cell motility 44.4444 4 no
GO:0032970 regulation of actin filament-based process 40.7407 4 no
GO:0071705 nitrogen compound transport 40.7407 4 no
GO:0010647 positive regulation of cell communication 40.7407 5 no
GO:0030155 regulation of cell adhesion 40.7407 4 no
GO:0031344 regulation of cell projection organization 40.7407 5 no
GO:0033043 regulation of organelle organization 40.7407 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 40.7407 5 no
GO:0060627 regulation of vesicle-mediated transport 40.7407 4 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 40.7407 6 no
GO:0023056 positive regulation of signaling 37.0370 4 no
GO:0051094 positive regulation of developmental process 37.0370 4 no
GO:0120036 plasma membrane bounded cell projection organization 37.0370 5 no
GO:0022604 regulation of cell morphogenesis 37.0370 5 yes
GO:0097435 supramolecular fiber organization 37.0370 4 no
GO:0051050 positive regulation of transport 37.0370 4 no
GO:0061024 membrane organization 37.0370 4 no
GO:0032880 regulation of protein localization 37.0370 5 no
GO:0060341 regulation of cellular localization 37.0370 4 no
GO:0030335 positive regulation of cell migration 37.0370 6 no
GO:0032956 regulation of actin cytoskeleton organization 37.0370 5 no
GO:0040017 positive regulation of locomotion 37.0370 4 no
GO:0044087 regulation of cellular component biogenesis 37.0370 4 no
GO:0051493 regulation of cytoskeleton organization 37.0370 6 no
GO:2000147 positive regulation of cell motility 37.0370 5 no
GO:0051130 positive regulation of cellular component organization 33.3333 5 no
GO:0007264 small GTPase mediated signal transduction 33.3333 4 no
GO:0009967 positive regulation of signal transduction 33.3333 5 no
GO:0008360 regulation of cell shape 33.3333 6 yes
GO:0007015 actin filament organization 33.3333 5 no
GO:0010628 positive regulation of gene expression 33.3333 6 no
GO:0045785 positive regulation of cell adhesion 33.3333 5 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0007265 Ras protein signal transduction 29.6296 5 no
GO:0030865 cortical cytoskeleton organization 29.6296 6 no
GO:0031325 positive regulation of cellular metabolic process 29.6296 5 no
GO:0042127 regulation of cell population proliferation 29.6296 4 no
GO:0045595 regulation of cell differentiation 29.6296 4 no
GO:1902533 positive regulation of intracellular signal transduction 29.6296 6 no
GO:0031175 neuron projection development 29.6296 6 no
GO:0015031 protein transport 29.6296 4 no
GO:0034330 cell junction organization 29.6296 4 no
GO:1903829 positive regulation of protein localization 29.6296 5 no
GO:0051247 positive regulation of protein metabolic process 29.6296 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 25.9259 5 no
GO:0044089 positive regulation of cellular component biogenesis 25.9259 5 no
GO:0002684 positive regulation of immune system process 25.9259 4 no
GO:0010941 regulation of cell death 25.9259 4 no
GO:0019220 regulation of phosphate metabolic process 25.9259 6 no
GO:0042325 regulation of phosphorylation 25.9259 7 no
GO:0042981 regulation of apoptotic process 25.9259 6 no
GO:0043067 regulation of programmed cell death 25.9259 5 no
GO:0045597 positive regulation of cell differentiation 25.9259 5 no
GO:0051174 regulation of phosphorus metabolic process 25.9259 5 no
GO:0051240 positive regulation of multicellular organismal process 25.9259 4 no
GO:1901701 cellular response to oxygen-containing compound 25.9259 4 no
GO:0050776 regulation of immune response 25.9259 4 no
GO:0008284 positive regulation of cell population proliferation 25.9259 5 no
GO:0051046 regulation of secretion 25.9259 5 no
GO:1903530 regulation of secretion by cell 25.9259 4 no
GO:0030031 cell projection assembly 25.9259 5 no
GO:1905475 regulation of protein localization to membrane 25.9259 6 no
GO:0032535 regulation of cellular component size 25.9259 4 no
GO:0060491 regulation of cell projection assembly 25.9259 5 no
GO:0120032 regulation of plasma membrane bounded cell projection assembly 25.9259 6 no
GO:0009889 regulation of biosynthetic process 22.2222 4 no
GO:0010632 regulation of epithelial cell migration 22.2222 4 no
GO:0031326 regulation of cellular biosynthetic process 22.2222 5 no
GO:0031346 positive regulation of cell projection organization 22.2222 6 no
GO:0001932 regulation of protein phosphorylation 22.2222 7 no
GO:0010243 response to organonitrogen compound 22.2222 4 no
GO:0010562 positive regulation of phosphorus metabolic process 22.2222 6 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0042327 positive regulation of phosphorylation 22.2222 8 no
GO:0043085 positive regulation of catalytic activity 22.2222 4 no
GO:0045937 positive regulation of phosphate metabolic process 22.2222 7 no
GO:1903076 regulation of protein localization to plasma membrane 22.2222 7 no
GO:1904375 regulation of protein localization to cell periphery 22.2222 6 no
GO:0006897 endocytosis 22.2222 5 no
GO:0043269 regulation of ion transport 22.2222 5 no
GO:0072657 protein localization to membrane 22.2222 4 no
GO:0072659 protein localization to plasma membrane 22.2222 5 no
GO:1990778 protein localization to cell periphery 22.2222 5 no
GO:0022407 regulation of cell-cell adhesion 22.2222 5 no
GO:0051222 positive regulation of protein transport 22.2222 5 no
GO:0051223 regulation of protein transport 22.2222 5 no
GO:0070201 regulation of establishment of protein localization 22.2222 6 no
GO:1904951 positive regulation of establishment of protein localization 22.2222 6 no
GO:0043254 regulation of protein-containing complex assembly 22.2222 5 no
GO:0051129 negative regulation of cellular component organization 22.2222 5 no
GO:0051726 regulation of cell cycle 22.2222 4 no
GO:0110053 regulation of actin filament organization 22.2222 6 no
GO:1902903 regulation of supramolecular fiber organization 22.2222 5 no

Disease

Term Name % Distance from top the of the tree Annotated in PALM2_HUMAN
DOID:0111962 combined immunodeficiency 7.4074 4 no
DOID:612 primary immunodeficiency disease 7.4074 3 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
AP3M1_HUMAN [view interactions] High throughput no yes
MSPD2_HUMAN [view interactions] High throughput no yes
LACC1_HUMAN [view interactions] High throughput no yes
ANK3_HUMAN [view entry] [view interactions] High throughput yes yes
SYT5_HUMAN [view entry] [view interactions] High throughput yes no
KCRM_HUMAN [view interactions] High throughput no no
OPTN_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
CTDSL_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
ANK2_HUMAN [view entry] [view interactions] High throughput yes yes
GPD1L_HUMAN [view interactions] High throughput no no
FOLC_HUMAN [view interactions] High throughput no no
E2AK4_HUMAN [view interactions] High throughput no yes
TES_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
ATE1_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
RND3_HUMAN [view interactions] High throughput no no
RHOJ_HUMAN [view interactions] High throughput no yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
LACB2_HUMAN [view interactions] High throughput no yes
KYNU_HUMAN [view interactions] High throughput no no
C10_HUMAN [view interactions] High throughput no yes
NIF3L_HUMAN [view interactions] High throughput no yes
NHRF1_HUMAN [view interactions] High throughput no no
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
CXAR_HUMAN [view interactions] High throughput no yes
DIRA3_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
E41LA_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
LAMP1_HUMAN [view interactions] High throughput no yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
LCK_HUMAN [view entry] [view interactions] High throughput yes no
LYN_HUMAN [view entry] [view interactions] High throughput yes no
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
OCLN_HUMAN [view interactions] High throughput no no
PANX1_HUMAN [view interactions] High throughput no no
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
ZFPL1_HUMAN [view interactions] High throughput no yes
ZYX_HUMAN [view interactions] High throughput no no
DPP4_HUMAN [view interactions] High throughput no no
PML_HUMAN [view interactions] High throughput no yes