Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SYN3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

May be involved in the regulation of neurotransmitter release and synaptogenesis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in SYN3_HUMAN
GO:0017076 purine nucleotide binding 31.5789 4 yes
GO:0032555 purine ribonucleotide binding 31.5789 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 31.5789 4 yes
GO:0005524 ATP binding 26.3158 5 yes
GO:0030554 adenyl nucleotide binding 26.3158 5 yes
GO:0032559 adenyl ribonucleotide binding 26.3158 5 yes
GO:0019905 syntaxin binding 21.0526 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in SYN3_HUMAN
GO:0046903 secretion 73.6842 4 yes
GO:0023061 signal release 68.4211 4 yes
GO:0099643 signal release from synapse 68.4211 5 yes
GO:0016192 vesicle-mediated transport 68.4211 4 no
GO:0006836 neurotransmitter transport 57.8947 4 yes
GO:0010646 regulation of cell communication 57.8947 4 yes
GO:0006887 exocytosis 57.8947 4 no
GO:0048522 positive regulation of cellular process 52.6316 4 no
GO:0051049 regulation of transport 52.6316 4 no
GO:0007269 neurotransmitter secretion 47.3684 4 yes
GO:0050804 modulation of chemical synaptic transmission 47.3684 5 yes
GO:0099177 regulation of trans-synaptic signaling 47.3684 4 yes
GO:0071702 organic substance transport 47.3684 4 no
GO:0071705 nitrogen compound transport 47.3684 4 no
GO:0051128 regulation of cellular component organization 47.3684 4 no
GO:0008104 protein localization 42.1053 4 no
GO:0015031 protein transport 42.1053 4 no
GO:0051046 regulation of secretion 42.1053 5 no
GO:1903530 regulation of secretion by cell 42.1053 4 no
GO:0006996 organelle organization 36.8421 4 no
GO:0007268 chemical synaptic transmission 36.8421 6 no
GO:0045055 regulated exocytosis 36.8421 5 no
GO:0098916 anterograde trans-synaptic signaling 36.8421 5 no
GO:0099537 trans-synaptic signaling 36.8421 4 no
GO:0022607 cellular component assembly 36.8421 4 no
GO:0097479 synaptic vesicle localization 36.8421 4 yes
GO:0051050 positive regulation of transport 31.5789 4 no
GO:0016079 synaptic vesicle exocytosis 31.5789 4 no
GO:0017157 regulation of exocytosis 31.5789 5 no
GO:0060627 regulation of vesicle-mediated transport 31.5789 4 no
GO:0099003 vesicle-mediated transport in synapse 31.5789 5 no
GO:0043933 protein-containing complex organization 31.5789 4 no
GO:0010647 positive regulation of cell communication 31.5789 5 no
GO:0023056 positive regulation of signaling 31.5789 4 no
GO:0043269 regulation of ion transport 31.5789 5 no
GO:0006897 endocytosis 26.3158 5 no
GO:0046928 regulation of neurotransmitter secretion 26.3158 4 no
GO:0051588 regulation of neurotransmitter transport 26.3158 5 no
GO:0065003 protein-containing complex assembly 26.3158 5 no
GO:0097091 synaptic vesicle clustering 26.3158 5 yes
GO:0072657 protein localization to membrane 26.3158 4 no
GO:1990778 protein localization to cell periphery 26.3158 5 no
GO:0031323 regulation of cellular metabolic process 26.3158 4 no
GO:0031399 regulation of protein modification process 26.3158 6 no
GO:0032880 regulation of protein localization 26.3158 5 no
GO:0051171 regulation of nitrogen compound metabolic process 26.3158 4 no
GO:0051246 regulation of protein metabolic process 26.3158 5 no
GO:0060255 regulation of macromolecule metabolic process 26.3158 4 no
GO:0060341 regulation of cellular localization 26.3158 4 no
GO:0080090 regulation of primary metabolic process 26.3158 4 no
GO:1904062 regulation of cation transmembrane transport 21.0526 6 no
GO:0017156 calcium-ion regulated exocytosis 21.0526 6 no
GO:0031338 regulation of vesicle fusion 21.0526 5 no
GO:0033043 regulation of organelle organization 21.0526 5 no
GO:0034330 cell junction organization 21.0526 4 no
GO:0044087 regulation of cellular component biogenesis 21.0526 4 no
GO:0050808 synapse organization 21.0526 5 no
GO:0061024 membrane organization 21.0526 4 no
GO:0051130 positive regulation of cellular component organization 21.0526 5 no
GO:0050806 positive regulation of synaptic transmission 21.0526 5 no
GO:0009893 positive regulation of metabolic process 21.0526 4 no
GO:0010604 positive regulation of macromolecule metabolic process 21.0526 5 no
GO:0019220 regulation of phosphate metabolic process 21.0526 6 no
GO:0031325 positive regulation of cellular metabolic process 21.0526 5 no
GO:0031401 positive regulation of protein modification process 21.0526 7 no
GO:0043085 positive regulation of catalytic activity 21.0526 4 no
GO:0048523 negative regulation of cellular process 21.0526 4 no
GO:0050807 regulation of synapse organization 21.0526 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 21.0526 5 no
GO:0051174 regulation of phosphorus metabolic process 21.0526 5 no
GO:0051223 regulation of protein transport 21.0526 5 no
GO:0051247 positive regulation of protein metabolic process 21.0526 6 no
GO:0070201 regulation of establishment of protein localization 21.0526 6 no
GO:0010959 regulation of metal ion transport 21.0526 6 no
GO:0022898 regulation of transmembrane transporter activity 21.0526 4 no
GO:0034762 regulation of transmembrane transport 21.0526 4 no
GO:0034765 regulation of ion transmembrane transport 21.0526 5 no
GO:0032228 regulation of synaptic transmission, GABAergic 10.5263 6 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CAPON_HUMAN [view entry] [view interactions] Low throughput yes yes
SYN2_HUMAN [view entry] [view interactions] Low throughput yes no
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
SYN3_HUMAN [view entry] [view interactions] Low throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MET_HUMAN [view interactions] High throughput no yes
PIAS2_HUMAN [view interactions] High throughput no yes
MO4L2_HUMAN [view interactions] High throughput no yes
CI072_HUMAN [view interactions] High throughput no no
MO4L1_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
ZN248_HUMAN [view interactions] High throughput no yes
DUS2_HUMAN [view interactions] High throughput no no
LIN7C_HUMAN [view entry] [view interactions] Computational yes yes
VAMP2_HUMAN [view entry] [view interactions] Computational yes no
SYN1_HUMAN [view entry] [view interactions] Computational yes no
SYT1_HUMAN [view entry] [view interactions] Computational yes no
LIN7B_HUMAN [view entry] [view interactions] Computational yes no
TIMP4_HUMAN [view interactions] Computational no no
RAB3A_HUMAN [view entry] [view interactions] Computational yes yes
CPLX1_HUMAN [view entry] [view interactions] Computational yes yes
LIN7A_HUMAN [view entry] [view interactions] Computational yes yes
SNP25_HUMAN [view entry] [view interactions] Computational yes yes
APBA1_HUMAN [view interactions] Computational no no