CDKL2_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CDKL2_HUMAN |
|---|---|---|---|---|
| GO:0003779 | actin binding | 42.3077 | 4 | no |
| GO:0003723 | RNA binding | 34.6154 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.7692 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 30.7692 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 30.7692 | 4 | yes |
| GO:0045296 | cadherin binding | 30.7692 | 4 | no |
| GO:0005524 | ATP binding | 26.9231 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 26.9231 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 26.9231 | 5 | yes |
| GO:0016462 | pyrophosphatase activity | 23.0769 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 23.0769 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 23.0769 | 6 | no |
| GO:0016301 | kinase activity | 7.6923 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 7.6923 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CDKL2_HUMAN |
|---|---|---|---|---|
| GO:0022607 | cellular component assembly | 53.8462 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | no |
| GO:0006996 | organelle organization | 42.3077 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 42.3077 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 42.3077 | 4 | no |
| GO:0007010 | cytoskeleton organization | 38.4615 | 5 | no |
| GO:0043933 | protein-containing complex organization | 34.6154 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 34.6154 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 34.6154 | 4 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 30.7692 | 4 | no |
| GO:0008104 | protein localization | 30.7692 | 4 | no |
| GO:0010646 | regulation of cell communication | 30.7692 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 30.7692 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 30.7692 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 30.7692 | 4 | no |
| GO:0007015 | actin filament organization | 30.7692 | 5 | no |
| GO:0032970 | regulation of actin filament-based process | 30.7692 | 4 | no |
| GO:0033043 | regulation of organelle organization | 30.7692 | 5 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 30.7692 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 26.9231 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.9231 | 4 | no |
| GO:0010468 | regulation of gene expression | 26.9231 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 26.9231 | 5 | no |
| GO:0010639 | negative regulation of organelle organization | 26.9231 | 6 | no |
| GO:0032535 | regulation of cellular component size | 26.9231 | 4 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 26.9231 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 26.9231 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 26.9231 | 6 | no |
| GO:0110053 | regulation of actin filament organization | 26.9231 | 6 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.0769 | 5 | no |
| GO:0030030 | cell projection organization | 23.0769 | 4 | no |
| GO:0032271 | regulation of protein polymerization | 23.0769 | 6 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 23.0769 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 23.0769 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 23.0769 | 5 | no |
| GO:0008064 | regulation of actin polymerization or depolymerization | 23.0769 | 6 | no |
| GO:0030832 | regulation of actin filament length | 23.0769 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 23.0769 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.0769 | 4 | no |
| GO:0051494 | negative regulation of cytoskeleton organization | 23.0769 | 7 | no |
| GO:1902904 | negative regulation of supramolecular fiber organization | 23.0769 | 6 | no |
| GO:0034330 | cell junction organization | 23.0769 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 23.0769 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 23.0769 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.0769 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.0769 | 5 | no |
| GO:0043412 | macromolecule modification | 19.2308 | 4 | yes |
| GO:0036211 | protein modification process | 15.3846 | 4 | yes |
| GO:0006468 | protein phosphorylation | 11.5385 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 11.5385 | 4 | yes |
| GO:0016310 | phosphorylation | 11.5385 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| HS905_HUMAN | [view interactions] | High throughput | no | no |
| HS904_HUMAN | [view interactions] | High throughput | no | no |
| UTP18_HUMAN | [view interactions] | High throughput | no | yes |
| NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
| TR150_HUMAN | [view interactions] | High throughput | no | yes |
| DDX52_HUMAN | [view interactions] | High throughput | no | no |
| MRT4_HUMAN | [view interactions] | High throughput | no | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GBG12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CING_HUMAN | [view interactions] | High throughput | no | no |
| BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
| GAR1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM28_HUMAN | [view interactions] | High throughput | no | yes |
| DDX18_HUMAN | [view interactions] | High throughput | no | yes |
| RPF2_HUMAN | [view interactions] | High throughput | no | yes |
| PININ_HUMAN | [view interactions] | High throughput | no | yes |
| DDX47_HUMAN | [view interactions] | High throughput | no | yes |
| NAT10_HUMAN | [view interactions] | High throughput | no | yes |
| MMTA2_HUMAN | [view interactions] | High throughput | no | yes |
| PKP2_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| DDX54_HUMAN | [view interactions] | High throughput | no | yes |
| LS14A_HUMAN | [view interactions] | High throughput | no | yes |
| KRI1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPV_HUMAN | [view interactions] | High throughput | no | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCM1_HUMAN | [view interactions] | High throughput | no | yes |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| RRS1_HUMAN | [view interactions] | High throughput | no | yes |
| RRP5_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| M4K2_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEBPZ_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSRAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| ADDA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCM3_HUMAN | [view interactions] | High throughput | no | no |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| DKC1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1F_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KR111_HUMAN | [view interactions] | High throughput | no | no |
| FRY_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| CDK14_HUMAN | [view interactions] | High throughput | no | yes |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |