Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

MYD88_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed, PubMed, PubMed). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed, PubMed, PubMed). Increases IL-8 transcription (PubMed). Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses such as SARS-CoV-2, SARS-CoV and HIV-1, induces IL1B release through NLRP3 inflammasome activation (PubMed). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

Position Amino acid Mutation Disease Overlap with binding region
93 Leu Pro Immunodeficiency68(IMD68) -
196 Arg Cys Immunodeficiency68(IMD68) -

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in MYD88_HUMAN
GO:0017076 purine nucleotide binding 38.7097 4 no
GO:0032555 purine ribonucleotide binding 38.7097 4 no
GO:0035639 purine ribonucleoside triphosphate binding 38.7097 4 no
GO:0031625 ubiquitin protein ligase binding 35.4839 5 no
GO:0044389 ubiquitin-like protein ligase binding 35.4839 4 no
GO:0005524 ATP binding 35.4839 5 no
GO:0030554 adenyl nucleotide binding 35.4839 5 no
GO:0032559 adenyl ribonucleotide binding 35.4839 5 no
GO:0019900 kinase binding 29.0323 4 no
GO:0003723 RNA binding 22.5806 4 no
GO:0016301 kinase activity 22.5806 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 22.5806 4 no
GO:0045296 cadherin binding 22.5806 4 no
GO:0019901 protein kinase binding 22.5806 5 no
GO:0005126 cytokine receptor binding 16.1290 4 yes
GO:0070851 growth factor receptor binding 16.1290 4 yes
GO:0005149 interleukin-1 receptor binding 12.9032 5 yes
GO:0035325 Toll-like receptor binding 12.9032 4 yes
GO:0003953 NAD+ nucleosidase activity 9.6774 5 yes
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 9.6774 4 yes
GO:0032813 tumor necrosis factor receptor superfamily binding 9.6774 5 yes
GO:0005121 Toll binding 6.4516 4 yes
GO:0005123 death receptor binding 6.4516 6 yes
GO:0070976 TIR domain binding 6.4516 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in MYD88_HUMAN
GO:0010646 regulation of cell communication 77.4194 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 77.4194 4 yes
GO:0060255 regulation of macromolecule metabolic process 77.4194 4 yes
GO:0080090 regulation of primary metabolic process 77.4194 4 yes
GO:0009966 regulation of signal transduction 74.1935 4 yes
GO:0048522 positive regulation of cellular process 74.1935 4 yes
GO:0010468 regulation of gene expression 70.9677 5 yes
GO:0031323 regulation of cellular metabolic process 70.9677 4 yes
GO:0009889 regulation of biosynthetic process 67.7419 4 yes
GO:0031326 regulation of cellular biosynthetic process 67.7419 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 64.5161 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 64.5161 5 yes
GO:1902531 regulation of intracellular signal transduction 64.5161 5 yes
GO:0009893 positive regulation of metabolic process 61.2903 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 61.2903 5 yes
GO:0048584 positive regulation of response to stimulus 61.2903 4 yes
GO:0051252 regulation of RNA metabolic process 61.2903 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 61.2903 7 yes
GO:2001141 regulation of RNA biosynthetic process 61.2903 6 yes
GO:0006355 regulation of DNA-templated transcription 61.2903 6 yes
GO:0048523 negative regulation of cellular process 58.0645 4 yes
GO:0051246 regulation of protein metabolic process 58.0645 5 no
GO:0009967 positive regulation of signal transduction 54.8387 5 yes
GO:0010647 positive regulation of cell communication 54.8387 5 yes
GO:0023056 positive regulation of signaling 54.8387 4 yes
GO:0080134 regulation of response to stress 51.6129 4 yes
GO:0051128 regulation of cellular component organization 48.3871 4 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 48.3871 5 no
GO:1902533 positive regulation of intracellular signal transduction 45.1613 6 yes
GO:0036211 protein modification process 45.1613 4 no
GO:0043412 macromolecule modification 45.1613 4 no
GO:0051247 positive regulation of protein metabolic process 45.1613 6 no
GO:0009892 negative regulation of metabolic process 41.9355 4 yes
GO:0044087 regulation of cellular component biogenesis 41.9355 4 yes
GO:0051240 positive regulation of multicellular organismal process 41.9355 4 yes
GO:0031399 regulation of protein modification process 41.9355 6 no
GO:0010605 negative regulation of macromolecule metabolic process 38.7097 5 yes
GO:0010628 positive regulation of gene expression 38.7097 6 yes
GO:0080135 regulation of cellular response to stress 38.7097 4 yes
GO:0031325 positive regulation of cellular metabolic process 38.7097 5 no
GO:0001817 regulation of cytokine production 38.7097 4 yes
GO:0032101 regulation of response to external stimulus 35.4839 4 yes
GO:0043408 regulation of MAPK cascade 35.4839 6 yes
GO:0071310 cellular response to organic substance 35.4839 4 yes
GO:0010941 regulation of cell death 35.4839 4 no
GO:0043254 regulation of protein-containing complex assembly 32.2581 5 yes
GO:0050776 regulation of immune response 32.2581 4 yes
GO:0051130 positive regulation of cellular component organization 32.2581 5 yes
GO:0010648 negative regulation of cell communication 32.2581 5 no
GO:0023057 negative regulation of signaling 32.2581 4 no
GO:0031401 positive regulation of protein modification process 32.2581 7 no
GO:0033043 regulation of organelle organization 32.2581 5 no
GO:0042981 regulation of apoptotic process 32.2581 6 no
GO:0043067 regulation of programmed cell death 32.2581 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 32.2581 6 no
GO:0002684 positive regulation of immune system process 32.2581 4 yes
GO:0010243 response to organonitrogen compound 29.0323 4 yes
GO:0030334 regulation of cell migration 29.0323 5 yes
GO:0031324 negative regulation of cellular metabolic process 29.0323 5 yes
GO:0031347 regulation of defense response 29.0323 5 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 29.0323 4 yes
GO:0051092 positive regulation of NF-kappaB transcription factor activity 29.0323 5 yes
GO:1901701 cellular response to oxygen-containing compound 29.0323 4 yes
GO:2000145 regulation of cell motility 29.0323 4 yes
GO:0006796 phosphate-containing compound metabolic process 29.0323 4 no
GO:0006996 organelle organization 29.0323 4 no
GO:0001819 positive regulation of cytokine production 29.0323 5 yes
GO:0032872 regulation of stress-activated MAPK cascade 25.8065 6 yes
GO:0042127 regulation of cell population proliferation 25.8065 4 yes
GO:0044089 positive regulation of cellular component biogenesis 25.8065 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 25.8065 5 yes
GO:0070302 regulation of stress-activated protein kinase signaling cascade 25.8065 5 yes
GO:0009057 macromolecule catabolic process 25.8065 4 no
GO:0016310 phosphorylation 25.8065 5 no
GO:0001932 regulation of protein phosphorylation 25.8065 7 no
GO:0006954 inflammatory response 25.8065 4 no
GO:0019220 regulation of phosphate metabolic process 25.8065 6 no
GO:0042325 regulation of phosphorylation 25.8065 7 no
GO:0043085 positive regulation of catalytic activity 25.8065 4 no
GO:0051094 positive regulation of developmental process 25.8065 4 no
GO:0051174 regulation of phosphorus metabolic process 25.8065 5 no
GO:0022607 cellular component assembly 25.8065 4 no
GO:0043933 protein-containing complex organization 25.8065 4 no
GO:0009891 positive regulation of biosynthetic process 25.8065 5 no
GO:0009968 negative regulation of signal transduction 25.8065 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 25.8065 6 no
GO:0031328 positive regulation of cellular biosynthetic process 25.8065 6 no
GO:0048585 negative regulation of response to stimulus 25.8065 4 no
GO:0051254 positive regulation of RNA metabolic process 25.8065 6 no
GO:0006915 apoptotic process 25.8065 4 yes
GO:0016192 vesicle-mediated transport 22.5806 4 yes
GO:0019221 cytokine-mediated signaling pathway 22.5806 4 yes
GO:0033993 response to lipid 22.5806 4 yes
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 22.5806 6 yes
GO:0043410 positive regulation of MAPK cascade 22.5806 7 yes
GO:0050727 regulation of inflammatory response 22.5806 5 yes
GO:0008104 protein localization 22.5806 4 no
GO:0030162 regulation of proteolysis 22.5806 6 no
GO:0051336 regulation of hydrolase activity 22.5806 4 no
GO:0051338 regulation of transferase activity 22.5806 4 no
GO:0018193 peptidyl-amino acid modification 22.5806 5 no
GO:0045893 positive regulation of DNA-templated transcription 22.5806 7 no
GO:1902680 positive regulation of RNA biosynthetic process 22.5806 7 no
GO:1903508 positive regulation of nucleic acid-templated transcription 22.5806 8 no
GO:0031344 regulation of cell projection organization 22.5806 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.5806 6 no
GO:0008284 positive regulation of cell population proliferation 19.3548 5 yes
GO:0009894 regulation of catabolic process 19.3548 4 yes
GO:0031334 positive regulation of protein-containing complex assembly 19.3548 6 yes
GO:0032479 regulation of type I interferon production 19.3548 5 yes
GO:0032874 positive regulation of stress-activated MAPK cascade 19.3548 7 yes
GO:0034097 response to cytokine 19.3548 4 yes
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 19.3548 7 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 19.3548 6 yes
GO:0046328 regulation of JNK cascade 19.3548 7 yes
GO:0051253 negative regulation of RNA metabolic process 19.3548 6 yes
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 19.3548 6 yes
GO:0071396 cellular response to lipid 19.3548 5 yes
GO:0002221 pattern recognition receptor signaling pathway 19.3548 4 yes
GO:0010608 post-transcriptional regulation of gene expression 16.1290 6 yes
GO:0031329 regulation of cellular catabolic process 16.1290 5 yes
GO:0032496 response to lipopolysaccharide 16.1290 4 yes
GO:0032675 regulation of interleukin-6 production 16.1290 5 yes
GO:0032755 positive regulation of interleukin-6 production 16.1290 6 yes
GO:0046330 positive regulation of JNK cascade 16.1290 8 yes
GO:0050865 regulation of cell activation 16.1290 4 yes
GO:0050867 positive regulation of cell activation 16.1290 5 yes
GO:0051249 regulation of lymphocyte activation 16.1290 5 yes
GO:0051251 positive regulation of lymphocyte activation 16.1290 6 yes
GO:0051607 defense response to virus 16.1290 4 yes
GO:0140546 defense response to symbiont 16.1290 4 yes
GO:0002237 response to molecule of bacterial origin 16.1290 4 yes
GO:0002685 regulation of leukocyte migration 16.1290 4 yes
GO:0002694 regulation of leukocyte activation 16.1290 4 yes
GO:0002696 positive regulation of leukocyte activation 16.1290 5 yes
GO:0009895 negative regulation of catabolic process 12.9032 5 yes
GO:0032481 positive regulation of type I interferon production 12.9032 6 yes
GO:0032642 regulation of chemokine production 12.9032 5 yes
GO:0032722 positive regulation of chemokine production 12.9032 6 yes
GO:0042742 defense response to bacterium 12.9032 4 yes
GO:0070498 interleukin-1-mediated signaling pathway 12.9032 5 yes
GO:0070555 response to interleukin-1 12.9032 5 yes
GO:0071219 cellular response to molecule of bacterial origin 12.9032 4 yes
GO:0071222 cellular response to lipopolysaccharide 12.9032 5 yes
GO:0002224 toll-like receptor signaling pathway 12.9032 5 yes
GO:0008063 Toll signaling pathway 9.6774 4 yes
GO:0031330 negative regulation of cellular catabolic process 9.6774 6 yes
GO:0032494 response to peptidoglycan 9.6774 4 yes
GO:0032651 regulation of interleukin-1 beta production 9.6774 6 yes
GO:0032652 regulation of interleukin-1 production 9.6774 5 yes
GO:0032667 regulation of interleukin-23 production 9.6774 5 yes
GO:0032677 regulation of interleukin-8 production 9.6774 5 yes
GO:0032680 regulation of tumor necrosis factor production 9.6774 6 yes
GO:0032731 positive regulation of interleukin-1 beta production 9.6774 7 yes
GO:0032732 positive regulation of interleukin-1 production 9.6774 6 yes
GO:0032757 positive regulation of interleukin-8 production 9.6774 6 yes
GO:0032760 positive regulation of tumor necrosis factor production 9.6774 7 yes
GO:0032944 regulation of mononuclear cell proliferation 9.6774 6 yes
GO:0032946 positive regulation of mononuclear cell proliferation 9.6774 7 yes
GO:0050670 regulation of lymphocyte proliferation 9.6774 6 yes
GO:0050671 positive regulation of lymphocyte proliferation 9.6774 7 yes
GO:0050830 defense response to Gram-positive bacterium 9.6774 5 yes
GO:0070663 regulation of leukocyte proliferation 9.6774 5 yes
GO:0070665 positive regulation of leukocyte proliferation 9.6774 6 yes
GO:1900225 regulation of NLRP3 inflammasome complex assembly 9.6774 6 yes
GO:1902622 regulation of neutrophil migration 9.6774 5 yes
GO:1903311 regulation of mRNA metabolic process 9.6774 6 yes
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 9.6774 5 yes
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 9.6774 6 yes
GO:0000165 MAPK cascade 9.6774 4 yes
GO:0002064 epithelial cell development 9.6774 4 yes
GO:0002449 lymphocyte mediated immunity 9.6774 4 yes
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 9.6774 6 yes
GO:0009682 induced systemic resistance 6.4516 4 yes
GO:0016064 immunoglobulin mediated immune response 6.4516 6 yes
GO:0019724 B cell mediated immunity 6.4516 5 yes
GO:0031098 stress-activated protein kinase signaling cascade 6.4516 4 yes
GO:0031663 lipopolysaccharide-mediated signaling pathway 6.4516 4 yes
GO:0032660 regulation of interleukin-17 production 6.4516 5 yes
GO:0032740 positive regulation of interleukin-17 production 6.4516 6 yes
GO:0032747 positive regulation of interleukin-23 production 6.4516 6 yes
GO:0034158 toll-like receptor 8 signaling pathway 6.4516 6 yes
GO:0036230 granulocyte activation 6.4516 4 yes
GO:0042119 neutrophil activation 6.4516 5 yes
GO:0042832 defense response to protozoan 6.4516 4 yes
GO:0043488 regulation of mRNA stability 6.4516 4 yes
GO:0043489 RNA stabilization 6.4516 4 yes
GO:0048255 mRNA stabilization 6.4516 5 yes
GO:0048660 regulation of smooth muscle cell proliferation 6.4516 5 yes
GO:0048661 positive regulation of smooth muscle cell proliferation 6.4516 6 yes
GO:0051403 stress-activated MAPK cascade 6.4516 5 yes
GO:0051873 killing by host of symbiont cells 6.4516 4 yes
GO:0060337 type I interferon signaling pathway 6.4516 5 yes
GO:0061013 regulation of mRNA catabolic process 6.4516 6 yes
GO:0061028 establishment of endothelial barrier 6.4516 6 yes
GO:0070935 3-UTR-mediated mRNA stabilization 6.4516 6 yes
GO:0070942 neutrophil mediated cytotoxicity 6.4516 4 yes
GO:0070943 neutrophil-mediated killing of symbiont cell 6.4516 5 yes
GO:0070944 neutrophil-mediated killing of bacterium 6.4516 6 yes
GO:0071260 cellular response to mechanical stimulus 6.4516 4 yes
GO:0090557 establishment of endothelial intestinal barrier 6.4516 7 yes
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus 6.4516 4 yes
GO:1900015 regulation of cytokine production involved in inflammatory response 6.4516 5 yes
GO:1900017 positive regulation of cytokine production involved in inflammatory response 6.4516 6 yes
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly 6.4516 7 yes
GO:1902369 negative regulation of RNA catabolic process 6.4516 7 yes
GO:1902373 negative regulation of mRNA catabolic process 6.4516 7 yes
GO:1903312 negative regulation of mRNA metabolic process 6.4516 7 yes
GO:2000338 regulation of chemokine (C-X-C motif) ligand 1 production 6.4516 6 yes
GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 6.4516 6 yes
GO:0001885 endothelial cell development 6.4516 5 yes
GO:0002238 response to molecule of fungal origin 6.4516 4 yes
GO:0002275 myeloid cell activation involved in immune response 6.4516 4 yes
GO:0002283 neutrophil activation involved in immune response 6.4516 5 yes
GO:0002444 myeloid leukocyte mediated immunity 6.4516 4 yes
GO:0002446 neutrophil mediated immunity 6.4516 5 yes
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6.4516 4 yes
GO:0006909 phagocytosis 6.4516 5 yes
GO:0007254 JNK cascade 6.4516 6 yes

Disease

Term Name % Distance from top the of the tree Annotated in MYD88_HUMAN
DOID:0050686 organ system cancer 6.4516 3 yes
DOID:0050747 lymphoplasmacytic lymphoma 6.4516 8 yes
DOID:0060058 lymphoma 6.4516 5 yes
DOID:0060060 non-Hodgkin lymphoma 6.4516 6 yes
DOID:0060901 Waldenstroems macroglobulinemia 6.4516 9 yes
DOID:2531 hematologic cancer 6.4516 4 yes
DOID:707 B-cell lymphoma 6.4516 7 yes

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
IRAK4_HUMAN [view interactions] Low throughput no yes
TIRAP_HUMAN [view interactions] Low throughput no no
MYD88_HUMAN [view entry] [view interactions] Low throughput yes yes
SIAH1_HUMAN [view interactions] Low throughput no yes
FADD_HUMAN [view interactions] Low throughput no yes
SPOP_HUMAN [view interactions] Low throughput no no
IRAK3_HUMAN [view interactions] Low throughput no yes
IRAK1_HUMAN [view interactions] Low throughput no yes
IRAK2_HUMAN [view interactions] Low throughput no yes
TLR5_HUMAN [view interactions] Low throughput no no
STAP2_HUMAN [view interactions] Low throughput no yes
IKKB_HUMAN [view interactions] Low throughput no yes
CBLB_HUMAN [view interactions] Low throughput no yes
BTK_HUMAN [view interactions] Low throughput no no
DOCK8_HUMAN [view interactions] Low throughput no yes
BCAP_HUMAN [view interactions] Low throughput no no
TLR4_HUMAN [view interactions] Low throughput no yes
TRAF3_HUMAN [view entry] [view interactions] Low throughput yes yes
TRAF6_HUMAN [view interactions] Low throughput no yes
TLR2_HUMAN [view interactions] Low throughput no no
IRF1_HUMAN [view interactions] Low throughput no yes
TNIP1_HUMAN [view interactions] Low throughput no yes
CYH2_HUMAN [view entry] [view interactions] Low throughput yes yes
TLR10_HUMAN [view interactions] Low throughput no no
HDAC6_HUMAN [view interactions] Low throughput no yes
P85A_HUMAN [view interactions] Low throughput no yes
IRF5_HUMAN [view interactions] Low throughput no no
IRF7_HUMAN [view interactions] Low throughput no yes
IL1R1_HUMAN [view interactions] Low throughput no no
TR13B_HUMAN [view interactions] Low throughput no yes
SARM1_HUMAN [view interactions] Low throughput no yes
ILRL1_HUMAN [view interactions] Low throughput no no
KSYK_HUMAN [view interactions] Low throughput no no
FAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
PK3CD_HUMAN [view interactions] Low throughput no no
TRAF2_HUMAN [view interactions] Low throughput no yes
CAMLG_HUMAN [view interactions] Low throughput no yes
TLR9_HUMAN [view interactions] Low throughput no no
RAC1_HUMAN [view entry] [view interactions] Low throughput yes no
IL1AP_HUMAN [view entry] [view interactions] Low throughput yes yes
LRRF1_HUMAN [view interactions] Low throughput no yes
LRRF2_HUMAN [view interactions] Low throughput no yes
FLII_HUMAN [view entry] [view interactions] Low throughput yes yes
CISH_HUMAN [view interactions] Low throughput no yes
SQSTM_HUMAN [view interactions] Low throughput no yes
BIRC3_HUMAN [view interactions] Low throughput no no
RNF41_HUMAN [view interactions] Low throughput no yes
SMAD6_HUMAN [view interactions] Low throughput no no
SMUF1_HUMAN [view interactions] Low throughput no yes
BST2_HUMAN [view interactions] Low throughput no yes
IKKE_HUMAN [view interactions] Low throughput no yes
SASH1_HUMAN [view interactions] Low throughput no yes
IRF4_HUMAN [view interactions] Low throughput no no
CYLD_HUMAN [view entry] [view interactions] Low throughput yes yes
UBAP1_HUMAN [view interactions] Low throughput no yes
TS101_HUMAN [view entry] [view interactions] Low throughput yes yes
ATG5_HUMAN [view interactions] Low throughput no no
BANK1_HUMAN [view interactions] Low throughput no no
RN152_HUMAN [view interactions] Low throughput no no
TNR16_HUMAN [view entry] [view interactions] Low throughput yes no
ILRL2_HUMAN [view interactions] Low throughput no no
CITE2_HUMAN [view interactions] Low throughput no yes
TLR3_HUMAN [view interactions] Low throughput no yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
UBC9_HUMAN [view interactions] High throughput no yes
SMAD3_HUMAN [view interactions] High throughput no yes
MAL_HUMAN [view interactions] High throughput no no
THIO_HUMAN [view interactions] High throughput no yes
SIAH2_HUMAN [view interactions] High throughput no no
UBP7_HUMAN [view interactions] High throughput no yes
RPAC1_HUMAN [view interactions] High throughput no no
C1QR1_HUMAN [view interactions] High throughput no no
TLR7_HUMAN [view interactions] High throughput no no
RAGE_HUMAN [view entry] [view interactions] High throughput yes no
CSF1_HUMAN [view interactions] High throughput no no
MDM2_HUMAN [view interactions] High throughput no yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
PFKAL_HUMAN [view entry] [view interactions] High throughput yes yes
MBIP1_HUMAN [view interactions] High throughput no yes
NTAQ1_HUMAN [view interactions] High throughput no yes
ZNF35_HUMAN [view interactions] High throughput no no
SPOPL_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
PRP31_HUMAN [view interactions] High throughput no yes
TBB4B_HUMAN [view interactions] High throughput no yes
TBB5_HUMAN [view interactions] High throughput no yes
TBA1C_HUMAN [view interactions] High throughput no yes
ARL1_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
STK38_HUMAN [view entry] [view interactions] High throughput yes yes
ANM5_HUMAN [view entry] [view interactions] High throughput yes yes
TMOD3_HUMAN [view interactions] High throughput no yes
M3K7_HUMAN [view interactions] High throughput no yes
PELI1_HUMAN [view interactions] High throughput no yes
BECN1_HUMAN [view interactions] High throughput no yes
BCL2_HUMAN [view interactions] High throughput no no
HNRPL_HUMAN [view interactions] High throughput no yes
TBK1_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
TANK_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
TNAP3_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
INS_HUMAN [view interactions] High throughput no no
GLOD4_HUMAN [view entry] [view interactions] High throughput yes yes
ARMX6_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] Computational yes yes
CLC7A_HUMAN [view interactions] Computational no no
TAB3_HUMAN [view interactions] Computational no yes
TF65_HUMAN [view entry] [view interactions] Computational yes yes
NFKB1_HUMAN [view interactions] Computational no yes
CD14_HUMAN [view interactions] Computational no no
IL18_HUMAN [view interactions] Computational no yes
TAB2_HUMAN [view interactions] Computational no yes
TAB1_HUMAN [view interactions] Computational no yes
TLR1_HUMAN [view interactions] Computational no no
IKBA_HUMAN [view interactions] Computational no yes
IL10_HUMAN [view interactions] Computational no no
M4K4_HUMAN [view interactions] Computational no yes
HMGB1_HUMAN [view interactions] Computational no yes
IFNB_HUMAN [view interactions] Computational no no
TLR8_HUMAN [view interactions] Computational no no
PGS1_HUMAN [view interactions] Computational no no
TLR6_HUMAN [view interactions] Computational no no
TOLIP_HUMAN [view entry] [view interactions] Computational yes yes
S10A8_HUMAN [view interactions] Computational no no
IKKA_HUMAN [view interactions] Computational no yes
UB2V1_HUMAN [view entry] [view interactions] Computational yes no
IL33_HUMAN [view interactions] Computational no yes
TCAM2_HUMAN [view interactions] Computational no no
SRC_HUMAN [view entry] [view interactions] Computational yes no
NGF_HUMAN [view interactions] Computational no no
IRF3_HUMAN [view interactions] Computational no yes
M3K1_HUMAN [view interactions] Computational no yes
LY96_HUMAN [view interactions] Computational no no
IL1RA_HUMAN [view interactions] Computational no no
TNFA_HUMAN [view interactions] Computational no no
S10A9_HUMAN [view entry] [view interactions] Computational yes no
NFKB2_HUMAN [view interactions] Computational no yes
IL1A_HUMAN [view interactions] Computational no no
DHX36_HUMAN [view interactions] Computational no yes
CASP1_HUMAN [view interactions] Computational no yes
E2AK2_HUMAN [view entry] [view interactions] Computational yes yes
RIPK2_HUMAN [view interactions] Computational no yes
TCAM1_HUMAN [view interactions] Computational no yes
ECHP_HUMAN [view interactions] Computational no no
UN93B_HUMAN [view interactions] Computational no yes
UBE2N_HUMAN [view entry] [view interactions] Computational yes yes
TNR5_HUMAN [view interactions] Computational no no
IL1B_HUMAN [view interactions] Computational no no
MTOR_HUMAN [view entry] [view interactions] Computational yes yes
IL6_HUMAN [view interactions] Computational no no
DHX9_HUMAN [view interactions] Computational no yes